This website uses cookies to enhance your browsing experience, improve site performance, and gather analytics. By selecting 'Accept,' you consent to these cookies as described in our Privacy Policy.

HomeBrowseAboutFAQs
Log In
Sign Up
Dystonia

Interactions Between Striatum and Cerebellum in ADCY5 and PRRT2 Dystonias

Sponsored by Institut National de la Santé Et de la Recherche Médicale, France

About this trial

Last updated 7 years ago

Study ID

C16-128

Status

Unknown status

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18-75 Years
183+ Years
All
All

Trial Timing

Ended 3 years ago

What is this trial about?

The investigators will study the relationship between the basal ganglia and the cerebellum in dystonia by associating cerebellar stimulations with functional magnetic resonance imaging analysis.

What are the participation requirements?

Yes

Inclusion Criteria

- clinical diagnosis of Dystonia

- characterized ADCY5 or PRRT2 mutation

- must have a European Social Security card or a parent having an European Social Security card

- must be older than > 15 years 3 months

- must be able to give informed consent or, for minor patients, parents must be able to give informed consent

- must be able to comply with all study procedures, based on the judgment by the investigator(s).

No

Exclusion Criteria

- major depression or any major mental disorders (axis I disorders)

- neurologic disorder other than dystonia

- presence of pacemaker, intracardiac lines, implanted pumps or stimulators, or metal objects inside the eye or skull, cochlear implant

- Permanent makeup of lips or eyelids

- Black large tattoo close to the head

- Severe claustrophobia

- Current pregnancy or breast feeding

- Copper intrauterine device Subjects with one of the following exclusion criteria will not receive cerebellar stimulation

- Open scalp wounds or scalp infection,

- epilepsy or seizures

- Taking at the time of the study: ketamine, antidepressants, ganciclovir, ritonavir, amphetamines, antiemetic.