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Modification of Posttetanic Count (PTC) for Monitoring Deep Neuromuscular Block II

Sponsored by Rigshospitalet, Denmark

About this trial

Last updated 16 years ago

Study ID

PTC-II

Status

Completed

Type

Interventional

Phase

Phase 4

Placebo

No

Accepting

18 to 65 Years
All Sexes

Trial Timing

Started 20 years ago

What is this trial about?

The purpose of this study is to examine the relationship between post-tetanic count (PTC) and time to first response to Train of four (TOF) stimulation during deep neuromuscular blockade induced by rocuronium.

What are the participation requirements?

Inclusion Criteria

* ASA 1-3

* General anaesthesia >1 hour

* Surgery in supine position with possibility of monitoring the neuromuscular blockade at the thumb (n.ulnaris stimulation).

* Written informed content

Exclusion Criteria

* Neuromuscular disorders, hepatic and renal dysfunction

* Medication expected to interfere with the neuromuscular blocking agent

* Allergy to any medication used during anaesthesia

* Body weight less or exceeding 20% of the ideal body weight

* Pregnancy or breastfeeding