Study Through Imaging of Visceral Lymphoid Organs in Patients With SCID Who Have Recieved Bone Marrow Allograft
Sponsored by Association Pour l'Aide a la Recherche en Immunologie Pediatrique
About this trial
Last updated 4 years ago
Study ID
AARIP-01
Status
Completed
Type
Observational
Placebo
No
Accepting
18+ Years
All
Trial Timing
Ended 5 years ago
What is this trial about?
To investigate the presence of seconday of lymphoid organs in patients who underwent
allogenic hematopoietic stem cell transplantation 15 to 45 years ago.
The goal aims to assess the development of seconday lymphoid organs given the fact that the
absence of myeloablation these patients present a split chimerism between T lymphocytes and
the other leucocytes. Thus, they may not be able to generate seconday lymphoid organs.
Practically, whole body MRI is being used to visualise and quantify both mediastinal and
intraabdominal lymph nodes. Delta will be compared with those obtained in healthy age-matched
individuals. It is scheduled to include 15 patients and 15 controls.
What are the participation requirements?
Inclusion Criteria
- Patients with SCID transplanted 15-45 years ago
Exclusion Criteria
- None