Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth
Sponsored by University of Colorado, Denver
About this trial
Last updated 2 years ago
Study ID
Status
Type
Placebo
Accepting
Trial Timing
Ended a month ago
What is this trial about?
What are the Participation Requirements?
Inclusion Criteria (transgender females):
- Identify as a transgender female
- Age 13-16 years at the time of enrollment
- If on a gonadotropin releasing hormone analogue, > 6 months exposure
- Plan to start estradiol clinically in < 4 months
Inclusion Criteria (cisgender males and females):
- Males and females ages 13-16 years
Exclusion Criteria:
- Cognitive, psychiatric, or physical impairment resulting in inability to tolerate the
study procedures
- Antipsychotic medication use
- Type 1 or 2 diabetes (by medical history)
- Polycystic ovarian syndrome (PCOS for cisgender females)
- Hypertension (resting BP ≥ 140/90 mm/Hg)
- Weight> 400 lbs
- On oral progesterone medications (including oral progesterone or progestin, combined
oral contraceptives or etonogestrel implant)
- Pregnancy (for cisgender females)