Calcium Carbonate on Labor Induction

Sponsored by Wake Forest University Health Sciences

About this trial

Last updated 6 months ago

Study ID

IRB00107112

Status

Active not recruiting

Type

Interventional

Phase

N/A

Placebo

Accepting

18+ Years

Female

Trial Timing

Started 2 years ago

What is this trial about?

The investigators aim to evaluate the safety and efficacy of administering calcium carbonate to laboring participants undergoing labor inductions. The investigators hypothesize that calcium carbonate is a low-risk preventative measure to decrease oxytocin induction time and dosage, decrease the rate of labor dystocia, decrease the rate of cesarean deliveries, and demonstrate no differences in maternal or neonatal safety outcomes.

What are the participation requirements?

Inclusion Criteria

* Adult laboring patients ( ≥ 18 years of age)

* Able to speak and read English or Spanish (for historical cohort, preferred language should be English or Spanish)

* Singleton gestation

* Greater ≥ 37 weeks gestation in vertex presentation

* Present for induction of labor inclusive of medical indication, elective indication at greater than 39 weeks gestation, trial of labor after cesarean

* Receive standard-dose oxytocin during induction

Exclusion Criteria

* Participants will be excluded from the study if they do not meet the above inclusion criteria or they will be further excluded under the following circumstances:

* Known need for cesarean section prior to induction of labor

* Known allergy to calcium carbonate

* Known contraindication to taking calcium carbonate including renal calculus, high urine calcium levels, elevated serum calcium, low serum phosphate, achlorhydria, or suspected digoxin toxicity.

* Inability to tolerate oral intake (i.e., nausea/vomiting)

* Need to be nothing by mouth (NPO)