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The Effect of Propolis Administration on Cholesterol Level in Diabetic Type 2 Patients

Sponsored by Indonesia University

About this trial

Last updated a year ago

Study ID

24-10-1677

Status

Recruiting

Type

Interventional

Phase

Phase 4

Placebo

Yes

Accepting

35 to 59 Years
All Sexes

Trial Timing

Ended 9 months ago

What is this trial about?

The goal of this clinical trial is to learn if propolis administration works to change the level of Low Density Lipoprotein (LDL) and High Density Lipoprotein cholesterol (HDL) in diabetic type 2 patients. The main questions it aims to answer are: - Is giving 1 drops/ 10kg/ times, twice daily for 8 weeks will change the level of LDL and HDL level in diabetic type 2 patients compared to placebo? Researchers will compare propolis to a placebo (a look-alike substance that contains no drug) to see if propolis works to change LDL and HDL cholesterol level. Participants will: * Take propolis or a placebo, 2 times daily with given dose (1 drops/10 kg/times) every day for 2 months * Visit the sub-district health centre once every 2 weeks for checkups * Get their blood checked before and after intervention

What are the participation requirements?

Inclusion Criteria

* Controlled Diabetes Mellitus type 2 with HbA1c <7.5%

* BMI 23-35 kg/m2

* On anti-cholesterol therapy

Exclusion Criteria

* Using injection therapy (insulin or GLP-1 RA)

* History of bees product allergy

* Active smoker

* Consuming alcohol

* Altered liver (ALT>35 IU/L) and kidney (eGFR<90 mL/min) function

* Pregnant and breastfeeding women

* History of cardiovascular disease (heart attack, stroke)