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Breast Cancer
+3

Identifying Genes That Predict Recurrence in Women With Breast Cancer Treated With Chemotherapy

Sponsored by Eastern Cooperative Oncology Group

About this trial

Last updated 8 years ago

Study ID

CDR0000456426

Status

Completed

Type

Observational

Placebo

No

Accepting

18-75 Years
18 to 120 Years
Female
Female

Not accepting

Not accepting
Healthy Volunteers

Trial Timing

Ended 20 years ago

What is this trial about?

RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict whether cancer will come back after treatment. PURPOSE: This laboratory study is identifying genes that may help predict recurrence in women with breast cancer treated with chemotherapy.

What are the Participation Requirements?

DISEASE CHARACTERISTICS:

- Diagnosis of breast cancer

- Node positive OR high-risk node negative disease

- Tumor > 1.0 cm in diameter

- No locally advanced, inflammatory, or metastatic breast cancer

- Previously treated with 4 courses of anthracycline-containing chemotherapy (i.e.,
doxorubicin and docetaxel OR doxorubicin and cyclophosphamide)

- Enrolled on clinical trial ECOG-E2197

- Adequate tumor material available in ECOG Pathology Coordination Center

- Previously consented to future cancer-related research

- Hormone receptor status known

PATIENT CHARACTERISTICS:

- Female

- Menopausal status not specified

PRIOR CONCURRENT THERAPY:

- See Disease Characteristics